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can 2 browns make a blue?

 
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martin.farrington4



Joined: 31 Aug 2008
Posts: 3
Location: uk

PostPosted: Sun Aug 31, 2008 7:23 pm    Post subject: can 2 browns make a blue? Reply with quote

Can two brown eyed parents make a blue eyed child??
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blu3



Joined: 05 Apr 2008
Posts: 10
Location: Nottinghamshire

PostPosted: Sun Aug 31, 2008 8:28 pm    Post subject: Reply with quote

Yes they can make a blue eyed child! According to my biology degree husband!

If they are both carriers of the blue eyed gene which is recessive to the brown eyed gene then both parents will be brown eyed. On average a 1/4 of their children will be blue eyed. It is also possible for blue eyed parents to produce brown eyed children because there's another set of genes which are different from the blue/brown eyed genes which causes brown blotches in the iris. A few brown blotches makes the eyes look green, a lot makes them look brown, in all those cases the child is genetically blue eyed. I'm genetically blue eyed (green eyes), my husband has blue eyes and our eldest has brown eyes!

Teachers are warned not to tell parents that blue eyed parents can't produce brown eyed children!
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martin.farrington4



Joined: 31 Aug 2008
Posts: 3
Location: uk

PostPosted: Mon Sep 01, 2008 12:46 pm    Post subject: Reply with quote

Thanks for your reply 'blu3'

I am still confused....!!!

My dads mum has blue eyes and my dads dad has brown. My mums dad has blue eyes and my mums mum has brown eyes. Both my parents have brown eyes and dark brown hair. I have blue eyes and blond hair.

I have been doing a little research into this and th efollowing calculator shows that my parents could not have a blue eyed child.

http://museum.thetech.org/ugenetics/eyeCalc/eyecalculator.html

The following is also an extract from another post on another site....

'It is possible for two brown-eyed parents to have a child with a different eye color than theirs. For two brown-eyed parents to have a blue-eyed child, for example, the mother and father would need to pass on a pair of blue alleles each to their offspring. If this child were to get one green allele in this mix instead, s/he would have green eyes; however, if a brown allele is present, regardless of what the other three alleles are, the child would have brown eyes. '

This would tend to indicate that my parents could not have a blue eyed child ..... as brown is dominant and blue is recessive to other colours. Clearly my parents and their parents possess the dominant brown colouring

So what is the answer?

Hope you are able to assist in simple terms!

Thanks

M
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blu3



Joined: 05 Apr 2008
Posts: 10
Location: Nottinghamshire

PostPosted: Mon Sep 01, 2008 9:12 pm    Post subject: Reply with quote

Hi Martin,

I have no idea so I'm typing what my oh says in reply.

Quote:
You inherit the genes that control a character, in pairs, one from each parent. To have blue eyes, you need two blue eyed genes, if you have 2 brown genes you have brown eyes. If you have a brown gene from one parent and a blue from another, you end up with brown eyes because the brown gene always dominates the blue gene. Such a person is said to carry the blue gene because they can pass it on even though it is hidden. Fifty percent of these people's s.e.x cells carry the blue gene even though the person has brown eyes. If a sperm carrying the gene for blue eyes fertilises an egg carrying a blue gene then the resulting child will have blue eyes even though both their parents have brown eyes. He's a biology specialist, you have to read it a few times to get it!
I really hope this helps. He offered to do a genetic diagram but I don't think I can put it on here!

According to my oh:
Quote:
The green is not caused by an allele at the same locus (place) on the chromosome, it is caused by a different set of alleles at a different locus on the chromosome. An example would be blood groups. The site on the chromosome which controls the main ABO blood group can only have the A B or O gene in it. However people can be Rhesus + or Rhesus- which modifies the blood group but the Rhesus genes are at another site on a chromosome.

In a similar way, a blue eyed person can have their eye colour modified to green by a separate set of genes e.g my oh has blue eyes, I have green, our eldest has pale brown eyes, all three of us are genetically blue eyed except that my oh has no modification, I have a slight one and our daughter has a heavy modification by these other genes.


It's not as cut and dried as you think, that is why teachers can't say that blue eyed parents can't produce a brown eyed child because they can. Under simple Mendelian genetics it appears the rules are broken but there are two factors involved not one.

I need a paracetamol now, I don't know about you! Laughing

Louise
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thescruff
Moderator


Joined: 03 May 2003
Posts: 4605
Location: Bath

PostPosted: Mon Sep 01, 2008 9:36 pm    Post subject: Reply with quote

You could email it to me blu and I'll pass it on.
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martin.farrington4



Joined: 31 Aug 2008
Posts: 3
Location: uk

PostPosted: Tue Sep 02, 2008 5:51 am    Post subject: Reply with quote

Hi

thanks for your response... The Sscruff also sent the diagram which was also helpful. Easier to understand than some of the technical stuff I have read!

Martin
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